Publication: Maternal plasma has higher hormone levels in pregnancies conceived with infertility

Differences in First Trimester Maternal Metabolomic Profiles in Pregnancies Conceived from Fertility Treatments.

Sun T, Lee B, Kinchen J, Wang ET, Gonzalez TL, Chan JL, Rotter JI, Chen YI, Taylor K, Goodarzi MO, Rich SS, Farber CR, Williams J 3rd, Pisarska MD.

J Clin Endocrinol Metab. 2018 Nov 15. doi: 10.1210/jc.2018-01118.

Links

• PubMed ID: 30445606
• The Journal of Clinical Endocrinology & Metabolism

Highlights

• We looked at metabolites circulating in maternal blood (specifically plasma) around late first trimester of pregnancy.
• Hormone levels (beta-estradiol and progesterone) were higher in patients with infertility, compared to patients who did not receive fertility treatments.
• ELISA assays with maternal plasma confirmed these results.